This Course Consists of Three Case Studies:

1. Mixed Phenotype Acute Leukemia With PML‑RARα Positive
2. Philadelphia Chromosome Positive Chronic Myeloid Leukemia With 5Q Deletion At Diagnosis
3. Chromosome Y As A Marker For Sex Discrepancies In Patients With Organ Transplants

Preview Individual Articles:

• Article 1: Preview
• Article 2: Preview
• Article 3: Preview

At the completion of this course the reader will be able to:

1. ARTICLE 1: Describe mixed phenotype acute leukemia (MPAL), the statistics of the disease, and whether there's a treatment.
2. ARTICLE 1: Discuss the case report recalling the patient's initial lab results, bone morphology, cytogenetics & molecular patterns, and the patient's lineal course.
3. ARTICLE 2: Recall Chronic myelogenous leukemia (CML), its cytogenetic & molecular patterns, outlook for disease prognosis, and treatment options.
4. ARTICLE 2: Interpret the patient's initial laboratory results.
5. ARTICLE 2: Discuss the importance of the cytogenetic abnormality 5q- .
6. ARTICLE 3: Recall testing for common autosomal chromosomal aneuploidies and sex determination compared to traditional biochemical and sonographic screening.
7. ARTICLE 3: After reviewing the case study, recall the chromosomal discrepancies that can occur in a patient that received a previous transplant.